Causes include code signature errors, app translocation, damaged documents, and corrupted or incompatible preference file.
translocation
If you thought that App Translocation only happens to apps left in their original folders and not moved, and doesn’t happen after first run, this could come as a surprise.
What and where is the Gatekeeper app or service? The answer is that it’s a collaborative system or technology to check apps and ensure that only trusted software is run.
There’s more to the quarantine flag, as it’s not binary on/off, and app translocation can trap even notarized applications if you don’t move them right.
You unarchive a freshly downloaded app and try to give it a test run. It immediately crashes. Here’s one common reason, and how to solve it very simply.
App translocation was introduced to stop malicious software exploiting relative file paths. So how come every time an iOS/iPadOS app is run, it’s translocated?
App translocation, signature checks, XProtect and more explained, with key messages from the log to help you diagnose problems.
Using Little Snitch, this becomes unresolvable, as the app can’t complete first run checks, and every time you try, it’s translocated to a different folder, causing Little Snitch to block it again.
The Eclectic Light Company 